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Bet on the LoL Mid-Season Invitational with Bitcoin at Cloudbet

The 2025 Mid-Season Invitational (MSI), held from June 27 to July 12 in Vancouver, Canada, is shaping up to be one of the biggest League of Legends tournaments of the year. Cloudbet is the #1 destination for betting on esports with Bitcoin and other cryptocurrencies. 

What is the LoL Mid-Season Invitational?

The Mid-Season Invitational (MSI) is Riot Games’ premier international League of Legends tournament held between the Spring and Summer splits. It features the top teams from every major region and serves as a mid-year benchmark ahead of Worlds.

While the format and number of teams can change year to year, MSI consistently delivers cross-regional matchups, evolving metas, and elite-level competition. It’s one of two Riot-sanctioned global events and a staple for fans and bettors alike.

What’s new in MSI 2025? 

The Mid‑Season Invitational pits 10 teams from the LPL, LCK, LEC, LTA, and LCP against each other for a $2 million prize pool. The MSI champion qualifies directly for Worlds 2025—provided they reach their Summer playoffs—and the runner-up’s region earns an extra Worlds seed.

MSI starts with a 4‑team Play‑In (double‑elim Bo5), then shifts to the 8‑team Bracket Stage (double‑elim Bo5). New this year is Fearless Draft—once a champion is picked in a best-of-five series, it’s off-limits for both teams for the rest of that match. This rule applies throughout the tournament — both Play-In and Bracket Stage — forcing deeper pools and bold draft strategies.

Who to bet on in the 2025 League of Legends MSI?

MSI 2025 brings a stacked lineup of LoL teams with something to prove on the international stage. Here are the top LoL teams to watch in 2025:

  1. Gen.G: Coming off their LCK Spring title, Gen.G enters MSI as the favorite. They have a clean 18-0 season record coming into the competition.
  2. G2 Esports: The kings of Europe are back. They lost the top seed to KOI but are EMEA favorites because of their veteran roster. 
  3. Bilibili Gaming: China’s #2 seed but arguably the most dangerous team on paper. 
  4. T1: Faker and crew return to the global stage with something to prove. Their disciplined teamfighting and late-game composure make the reigning world champions a perennial threat.
  5. FlyQuest: North America’s number one seed heads to MSI after besting Cloud9 for the LTA North title with a controversial backdoor play.

Other popular LoL tournaments to bet on

League of Legends runs on a seasonal calendar anchored by a few global events. While regional leagues like the LCK, LPL, and LEC draw steady action, the international showdowns are where the betting really heats up. 

Here are other tournaments for LoL bettors:

  1. League of Legends World Championship (Worlds): The crown jewel of LoL esports, held every fall. All roads lead here.
  2. LPL, LCK, LEC, and LTA playoffs: Regional title fights with international implications. High-level matchups, fierce rivalries, and high-volume betting.(Note: LTA now includes teams from former LCS, CBLOL, and LLA regions.)
  3. Special appearances: LoL is also featured in multi-title events like the Asian Games and Olympic Esports Week, where national teams compete. 

Top tips to bet on the Mid-Season Invitational

MSI offers high stakes and high variance. With top teams from different regions clashing in unfamiliar matchups, sharp betting can give you a serious edge. Here’s how to play it smart:

  1. Check regional performance trends: LPL and LCK teams often come in hot, but EU or NA squads can thrive on the underdog tag. Look for patterns in playstyle and adaptability.
  2. Draft phase matters: Some teams draft for early game pressure, others for scaling. Watch how confident they are on red vs. blue side and how often they win draft.
  3. Live betting edge: LoL momentum swings fast — especially at MSI. Bet during pauses or between games to take advantage of odds that lag behind gameplay reality.
  4. Mind the tilt factor: One bad game can snowball into a series loss. Teams with strong mental game — or veteran leadership — are more likely to bounce back mid-series.
  5. Don’t chase: Set a crypto betting budget before the tourney. Stick to it, even if your favorite team loses a heartbreaker.

MSI is where reputations are made and metas are tested. With sharp eyes and disciplined bets, you can ride the action and capitalize on every moment.

Types of MSI bets

Cloudbet covers all the most popular betting markets for League of Legends matches:

  1. Match Winner: Bet on which team wins the best-of series
  2. Map Winner: Pick who takes a specific game . 
  3. Map Handicap: Bet on the team's result per map.
  4. Total Maps: Bet on the total number of maps won by both teams. 

Betting on MSI at Cloudbet is simple:

  1. Sign up for a Cloudbet account and fund your account wallet with Bitcoin or any of the 30+ cryptocurrencies available.
  2. Head to the esports section and select 'League of Legends.’ Here you'll find odds and lines for upcoming matches, tournaments, and other competitions.
  3. Research teams, players, and trends to make informed LoL bets. You can also bet in-play, wagering on matches as they happen.
  4. Place your LoL bets and watch the action unfold! Cloudbet offers fast payouts directly to your account wallet.

No matter the tournament, league, or match, Cloudbet provides the most betting markets on all things LoL. Bet on money lines, props, and more. Take advantage of live, in-play betting for added excitement.

For esports fans who want to bet on the thrilling action of LoL with crypto, Cloudbet is the ultimate online sportsbook.

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